Follow Us:Respiratio 2023; 13, (1-2): 136-144
FAKTORI KOJI DETERMINIŠU POSTOPERATIVNI PERIOD PREŽIVLJAVANJA NAKON OPERATIVNOG LIJEČENJA PRIMARNIH TUMORA MOZGA - STUDIJA PRESJEKA
DETERMINING FACTORS OF THE POSTOPERATIVE SURVIVAL PERIOD AFTER SURGICAL TREATMENT OF PRIMARY BRAIN TUMORS –
A CROSS-SECTION STUDY
Vesna Ivanišević1,3 , Mišo Miškić1, Saša Dragić2,3, Danica Momčičević2,3, 
Biljana Zlojutro2,3, Milka Jandrić2,3, Peđa Kovačević2,3
1 Klinika za neurohirurgiju, Univerzitetski klinički centar Republike Srpske
1 Neurosurgery Clinic, University of Clinical Center Republic of Srpska
2 Klinika intenzivne medicine za nehirurške grane, Univerzitetski klinički centar Republike Srpske
2 Medical Intensive Care Unit, University of Clinical Center Republic of Srpska
3Medicinski fakultet, Univerzitet u Banjoj Luci
3Faculty of Medicine, University of Banja Luka
Original Research
Naučni članak
Sažetak
Uvod: Primarni tumori mozga čine 50-60% svih intrakranijalnih tumora kod odraslih. Oni vode porijeklo od ćelijskih elemenata moždanog parenhima i epifize, te su po lokalizaciji najčešće intracerebralni, mada neki tipovi imaju tendenciju rasta unutar moždanih komora ili u pravcu subarahnoidalnog prostora.
Cilj: Utvrditi karakteristike operativno liječenih pacijenata, te ispitati korelaciju između dužine postoperativnog preživljavanja pacijenata i pola, starosne dobi, vrste tumora i vrste primjenjenog hirurškog tretmana.
Metode: Sprovedena je retrospektivna studija presjeka na osnovu podataka preuzetih iz kliničkog informacionog Sistema u Univerzitetskom kliničkom centru Republike Srpske i to u periodu od 01.01.2018. do 31.12.2019. godine. Osim pola i starosne dobi u uzorku je evidentirana i vrsta tumora prema patohistološkoj klasifikaciji, pojava i učestalost najčešćih simptoma, vrsta primjenjenog hirurškog tretmana, broj reintervencija i dužina postoperativnog preživljavanja. Podaci su obrađeni primjenom statistilčkog SPSS 21 programa.
Rezultati: U ovu studiju je uključeno 115 operativno liječenih pacijenata, prosječne dobi 57.55 godina, od toga 45.2% žena. Najveći broj ispitanika je bio u dobi 35-65 godina (65.2%). Od svih patohistoloških tipova, najviše je bilo difuznih glijalnih tumora (76.5%). Najčešći simptom kod pacijenata je bila glavobolja sa učestalošću 80.9%, a najčešća primjenjena intervencija je bila parcijalna redukcija tumora (51.5%), dok samo 53.9% ispitanika preživi do 1 godinu po operaciji. χ2 testom je utvrđeno da postoji statistički značajna veza između perioda postoperativnog preživljavanja pacijenata i dobi (p=0.000); vrste glioma (p=0.000); vrste glijalnog difuznog tumora (p=0.000) i vrste hirurškog tretmana (p=0.000).
Zaključak: Iako je problematika operativnog liječenja tumora mozga dosta složena i pristup svakom pacijentu je individualan, postoje određene karakteristike koje su udružene sa boljom ili lošijom prognozom, dok se prema rezultatima ove studije izdvajaju dob, patohistološki tip tumora i tip operativnog pristupa kao osnovne determinante postoperativnog perioda preživljavanja.
Ključne riječi: primarni tumori mozga, intracerebralni tumori, postoperativni period preživljavanja
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Kontakt:
Vesna Ivanišević
Univerzitetski klinički centar Republike Stpske
Klinika za neurohirurgiju
Tel.: + 387 66 915 165
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.